Article
A postulated phylogenetic tree for the human apolipoprotein B gene: unpredicted haplotypes are associated with elevated apo B levels.
Biochimica et biophysica acta - 10 Jan 1993
Dunning A M, Renges H H, Hamsten A, Talmud P, Humphries S
Abstract excerpt
Using published data on seven polymorphic sites in the human apolipoprotein B (apo B) gene, it is possible to postulate a model phylogenetic tree for this gene, covering the time since the divergence of human beings from other primates. This simple model assumes no obligatory recombination events...
Topics
- Amino Acid Sequence
- Apolipoproteins B
- Female
- Gene Expression
- Genotype
- Haplotypes
- Humans
- Male
- Models, Genetic
- Molecular Sequence Data
- Myocardial Infarction
- Polymorphism, Restriction Fragment Length
- Protein Sorting Signals