Article
Osteogenesis imperfecta in Holstein-Friesian calves.
Zentralblatt fur Veterinarmedizin. Reihe A - 1 Mar 1994
Agerholm J S, Lund A M, Bloch B, Reibel J, Basse A, Arnbjerg J
Abstract excerpt
Eight calves with osteogenesis imperfecta were born in a Danish Holstein-Friesian herd during a two-year period. In total 92 calves were born (84 normal), and all were sired by a clinically normal Holstein-Friesian bull. The defect was probably due to a de novo dominant mutation present as a gonadal mosaicism in the bull. Affected calves were characterised by multiple fractures, congenital bone deformations,...
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