Article
[Study of sex determination gene (SRY) in 46,XY gonadal dysgenesis].
Annales d'endocrinologie - 1 Jan 1994
Boucekkine C, Vilain E, McElreavey K, Jaubert F, Brauner R, Thibaud E, Battin J, Toublanc J E, Kucheria K, Chaabouni S
Abstract excerpt
During mammalian embryogenesis, the presence of the SRY gene determines the bipotential gonad to develop as a testis. 46,XY sex reversal has been described in man. It is associated with an essentially female phenotype and a streak gonad. In a collaborative study, we analysed 36 patients with a 46...
Topics
- DNA-Binding Proteins
- Female
- Gene Deletion
- Genes
- Genotype
- Gonadal Dysgenesis, 46,XY
- Humans
- Kruppel-Like Transcription Factors
- Male
- Point Mutation
- Transcription Factors