Article
Malignant lymphoma of the urethra: report of a case with detection of Epstein-Barr virus genome in the tumour cells.
Histopathology - 1 Jun 1994
Ohsawa M, Mishima K, Suzuki A, Hagino K, Doi J, Aozasa K
Abstract excerpt
We report a primary non-Hodgkin's B-cell lymphoma of the urethra in a 78-year-old female. Serum antibodies for Epstein-Barr virus (EBV) were negative, but there was a 40-fold increase in antibodies to EBV-associated nuclear antigen. Using PCR and in situ hybridization techniques, EBV genome was f...
Topics
- Aged
- Antibodies, Viral
- Antigens, Viral
- DNA-Binding Proteins
- Electrophoresis, Agar Gel
- Epstein-Barr Virus Nuclear Antigens
- Female
- Fluorescent Antibody Technique
- Genome, Viral
- Herpesviridae Infections
- Herpesvirus 4, Human
- Humans
- Immunohistochemistry
- In Situ Hybridization
- Lymphoma, B-Cell
- Phenotype
- Polymerase Chain Reaction
- Tumor Cells, Cultured