alpha-1-Antitrypsin phenotypes among breast cancer patients in the Basque population.

doi:10.1159/000154218

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Article

alpha-1-Antitrypsin phenotypes among breast cancer patients in the Basque population.

Human heredity - 1 Jan 2000

García-Orad A, Arizti P, Durán L, Urcelay B, de Pancorbo M M

Abstract excerpt

One of the main functions of alpha 1-antitrypsin (A1AT) is to inhibit the activity of most proteases. It has been suggested that a deficiency in this protein may favor invasion by cancer cells--consequently, individuals with A1AT-deficient alleles (null, S and Z) may be at greater risk of tumoral...

Topics

Adult
Alleles
Breast Neoplasms
Carcinoma, Ductal, Breast
Female
Gene Frequency
Humans
Isoelectric Focusing
Phenotype
Spain
alpha 1-Antitrypsin
alpha 1-Antitrypsin Deficiency

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