The Role of Sunlight and DNA Repair in Melanoma and Nonmelanoma Skin Cancer

Abstract excerpt

BACKGROUND AND DESIGN: The frequency of melanoma and nonmelanoma skin cancer is increasing rapidly in the United States. However, the linkage of these cancers to sun exposure has been questioned because of differences in anatomic site distribution. To obtain insights into the development of these skin cancers, we examined reports of 132 patients with xeroderma pigmentosum (XP), an inherited cancer-prone, DNA...

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