Genetic control of erythrocyte volume regulation: effect of a single gene (rol) on cation metabolism.

doi:10.1152/ajpcell.1994.267.1.C211

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Article

Genetic control of erythrocyte volume regulation: effect of a single gene (rol) on cation metabolism.

The American journal of physiology - 1 Jul 1994

Fernandes P R, Dewey M J

Abstract excerpt

In laboratory mice we previously defined a gene, rol (resistance to osmotic lysis), based on its effect on erythrocyte osmotic fragility. Here we report a physiological characterization of rol gene action utilizing congenic strains developed for the purpose; these two strains have a common genetic background and differ only by the two alleles of rol, susceptible (rols) or resistant (rolr). In comparison to rols/s...

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