Article
Identification of mutations in the putative ATP-binding domain of the adrenoleukodystrophy gene.
The Journal of clinical investigation - 1 Aug 1994
Fanen P, Guidoux S, Sarde C O, Mandel J L, Goossens M, Aubourg P
Abstract excerpt
The recently identified adrenoleukodystrophy (ALD) gene is predicted to encode a peroxisomal protein of 745 amino acids that includes one domain for ATP-binding, termed nucleotide-binding fold (NBF). To determine whether mutations occur in the putative NBF of ALD protein, we analyzed by denaturin...
Topics
- ATP Binding Cassette Transporter, Subfamily D, Member 1
- ATP-Binding Cassette Transporters
- Adenosine Triphosphate
- Adrenoleukodystrophy
- Amino Acid Sequence
- Base Sequence
- Binding Sites
- Carrier Proteins
- Exons
- Humans
- Membrane Proteins