Flow rate of cerebrospinal fluid (CSF)--a concept common to normal blood-CSF barrier function and to dysfunction in neurological diseases.

doi:10.1016/0022-510x(94)90298-4

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Article

Flow rate of cerebrospinal fluid (CSF)--a concept common to normal blood-CSF barrier function and to dysfunction in neurological diseases.

Journal of the neurological sciences - 1 Apr 1994

Reiber H

Abstract excerpt

Many neurological diseases are accompanied by increased protein concentrations in the cerebrospinal fluid (CSF), described as a blood-CSF barrier dysfunction. The earlier interpretation as a "leakage" of the blood-CSF barrier for serum proteins could be revised by introduction of a "population variation coefficient" of the CSF/serum quotients for IgG, IgA and IgM (delta Q/Q) which is evaluated as a function of...

Topics

Adolescent
Adult
Aged
Animals
Blood Proteins
Blood-Brain Barrier
Cerebrospinal Fluid
Cerebrospinal Fluid Proteins
Child
Child, Preschool
Diffusion
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Variation

Humans

Immunoglobulins

Infant

Male

Middle Aged

Source

Open in PubMed

Identifiers

PMID: 8021703
DOI: 10.1016/0022-510x(94)90298-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8021703-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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