Article
Abnormal processing of a recombinant feline leukemia virus envelope polyprotein and its interference with subgroup C virus infection.
Virology - 1 Jul 1994
Bechtel M K, Stallcup M R, Bedgood R M, Corey J L, Pandey R, Roy-Burman P
Abstract excerpt
Processing of the env polyprotein of a noninfectious feline leukemia virus (FeLV) recombinant, named r6gp, was examined in human-transfected cells. The r6gp provirus was previously generated in the frame of FeLV, subgroup B, GA clone with substitution of all but 40 C-terminal amino acid sequences of the surface glycoprotein (SU) from an endogenous FeLV provirus element (CFE-6). Although r6gp produced a normal...
Topics
- Amino Acid Sequence
- Base Sequence
- Cloning, Molecular
- DNA, Viral
- Fluorescent Antibody Technique
- Humans
- Kinetics
- Leukemia Virus, Feline
- Molecular Sequence Data
- Mutation
- Protein Processing, Post-Translational
