Article
How is it that microsatellites and random oligonucleotides uncover DNA fingerprint patterns?
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Sept 1994
Kashi Y, Nave A, Darvasi A, Gruenbaum Y, Soller M, Beckmann J S
Abstract excerpt
Minisatellites, microsatellites, and short random oligonucleotides all uncover highly polymorphic DNA fingerprint patterns in Southern analysis of genomic DNA that has been digested with a restriction enzyme having a 4-bp specificity. The polymorphic nature of the fragments is attributed to tandem repeat number variation of embedded minisatellite sequences. This explains why DNA fingerprint fragments are...
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