Article
Variation at the hepatic lipase and apolipoprotein AI/CIII/AIV loci is a major cause of genetically determined variation in plasma HDL cholesterol levels.
The Journal of clinical investigation - 1 Dec 1994
Cohen J C, Wang Z, Grundy S M, Stoesz M R, Guerra R
Abstract excerpt
Genetic factors have been shown to play an important role in determining interindividual variation in plasma HDL-C levels, but the specific genetic determinants of HDL cholesterol (HDL-C) levels have not been elucidated. In this study, the effects of variation in the genomic regions encoding hepa...
Topics
- Apolipoprotein A-I
- Apolipoprotein C-III
- Apolipoproteins
- Apolipoproteins A
- Apolipoproteins C
- Base Sequence
- Causality
- Cholesterol, HDL
- Genetic Variation
- Humans
- Lipase
- Liver
- Molecular Sequence Data
- Nuclear Family
- Statistics as Topic