Induction of c-fos and CRF mRNA by MK-801 in the parvocellular paraventricular nucleus of the rat hypothalamus.

doi:10.1016/0169-328x(94)90132-5

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Article

Induction of c-fos and CRF mRNA by MK-801 in the parvocellular paraventricular nucleus of the rat hypothalamus.

Brain research. Molecular brain research - 1 Jul 1994

Lee S, Rivier C, Torres G

Abstract excerpt

The non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist dizocilpine maleate (MK-801) stimulates the secretion of adrenocorticotropin hormone (ACTH). As corticotropin-releasing factor (CRF) represents the primary modulator of this secretion, we tested the hypothesis that the ability of...

Topics

Animals
Corticotropin-Releasing Hormone
Dizocilpine Maleate
Gene Expression
Genes, fos
Hypothalamo-Hypophyseal System
Immunohistochemistry
In Situ Hybridization
Male
Neurons
Paraventricular Hypothalamic Nucleus
Phenotype
Pituitary-Adrenal System
Proto-Oncogene Proteins c-fos
RNA, Messenger
Rats
Rats, Sprague-Dawley
Reference Values

Source

Open in PubMed

Identifiers

PMID: 7968357
DOI: 10.1016/0169-328x(94)90132-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7968357-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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