Article
Microsatellite markers and the analysis of genetic disease.
The British veterinary journal - 1 Jan 2000
Holmes N G
Abstract excerpt
The application of molecular biology is revolutionizing our understanding of the genetic contribution to disease in both man and animals. Candidate genes for a disorder can now be rapidly screened and sequenced. When no candidate gene is available, mutations can be localized to one particular region of a chromosome by positional cloning. This approach has been greatly facilitated by the development of...
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