Approaches to genetic studies of asthma.

doi:10.1164/ajrccm/150.5_Pt_2.S91

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Article

Approaches to genetic studies of asthma.

American journal of respiratory and critical care medicine - 1 Nov 1994

Meyers D A

Abstract excerpt

It is important to remember that any postulated linkage needs to be confirmed and the identification of one major locus does not mean that other major loci are not also present. The failure to replicate a postulated linkage has become a serious problem in studies on the genetics of complex disorders. A major reason for failure to replicate, as discussed by Risch (30) may be the interpretation of a LOD score...

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PMID: 7952602
DOI: 10.1164/ajrccm/150.5_Pt_2.S91

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