Use of cohorts with extensive longitudinal data in investigating the molecular genetics of asthma.

doi:10.1046/j.1365-2222.1998.0280s1046.x

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Use of cohorts with extensive longitudinal data in investigating the molecular genetics of asthma.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Apr 1998

Le Souëf P

Abstract excerpt

Recent studies have associated several chromosomal regions and specific polymorphisms with asthma, atopy and airway hyperresponsiveness. Most of these studies have been cross-sectional which substantially limits their power to analyse genotype/phenotype associations. Asthma is a such a highly variable condition that future genotype/phenotype studies should use longitudinal data. Populations with extensive...

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