Article
Analysis of the distribution and molecular heterogeneity of the ospD gene among the Lyme disease spirochetes: evidence for lateral gene exchange.
Journal of bacteriology - 1 Aug 1994
Marconi R T, Samuels D S, Landry R K, Garon C F
Abstract excerpt
Analysis of the ospD gene has revealed that this gene is not universal among Lyme disease spirochete isolates. The gene was found to be carried by 90, 50, and 24% of the Borrelia garinii, B. afzelii, and B. burgdorferi isolates tested. Size variability in the ospD-encoding plasmid was also observ...
Topics
- Amino Acid Sequence
- Animals
- Bacterial Outer Membrane Proteins
- Base Sequence
- Borrelia
- Borrelia burgdorferi Group
- Cloning, Molecular
- Genes, Bacterial
- Genetic Variation
- Humans
- Lyme Disease
- Molecular Sequence Data
- Polymorphism, Restriction Fragment Length
- Sequence Analysis, DNA
- Sequence Homology, Amino Acid
- Sequence Homology, Nucleic Acid