Article
Histidine 326 is critical for the function of GLT-1, a (Na+ + K+)-coupled glutamate transporter from rat brain.
The Journal of biological chemistry - 29 Jul 1994
Zhang Y, Pines G, Kanner B I
Abstract excerpt
Removal of glutamate from the synaptic cleft is carried out by transporter molecules located in presynaptic nerve terminals and fine glial processes surrounding the cleft. Three such transporters, which are approximately 55% identical to each other, have recently been cloned. They catalyze electrogenic transport of this neurotransmitter, which is coupled to the fluxes of three ions: sodium, potassium, and protons...
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