Frequent polymorphism in exon 15 of the adenomatous polyposis coli gene.

doi:10.1007/BF00212032

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Article

Frequent polymorphism in exon 15 of the adenomatous polyposis coli gene.

Human genetics - 1 Mar 1994

Davies S M, Snover D C

Abstract excerpt

In the course of a study of tumor suppressor gene mutation in hepatoblastoma, a frequent neutral polymorphism was identified at codon 1493 in exon 15 of the gene causing adenomatous polyposis coli (APC). As the polymorphism introduces a new BsaJ1 site, DNA amplified by the polymerase chain reacti...

Topics

Adenomatous Polyposis Coli
Alleles
Codon
Exons
Heterozygote
Humans
Polymerase Chain Reaction
Polymorphism, Restriction Fragment Length

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