Article
Molecular analysis of the glycoprotein C-negative phenotype of attenuated Marek's disease virus.
Virology - 1 Mar 1994
Wilson M R, Southwick R A, Pulaski J T, Tieber V L, Hong Y, Coussens P M
Abstract excerpt
Serial passage of oncogenic serotype 1 Marek's Disease virus (MDV) in cultured avian cells results in attenuation of viral oncogenicity and pathogenicity. Coincident with attenuation, expression of MDV glycoprotein C (gC) is significantly reduced. Regulation of MDV gC may have important implications for virus-host interactions and have important consequences in the process of viral attenuation. To investigate the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
