Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of a Marek's disease virus mutant containing a lacZ insertion in the US6 (gD) homologue gene.

Virus genes - 1 Sept 1994

Parcells M S, Anderson A S, Morgan R W

Abstract excerpt

We report the construction of a Marek's disease virus (MDV) mutant containing the lacZ gene of Escherichia coli inserted into a homologue of the US6 (glycoprotein D, gD) gene of herpes simplex virus. The mutant was constructed using the high-passage GAatt85 MDV strain as the parent virus, since that strain grows readily in chicken embryo fibroblasts using culture conditions conducive to mutant virus construction....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cells, Cultured
Share to Chickens
Share to Chromosome Mapping

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Transposable Elements

Share to Escherichia coli

Share to Genes, Viral

Share to Mutation

Share to Transcription, Genetic

Source

Identifiers

PMID: 7871761
DOI: 10.1007/BF01703430

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of a Marek's disease virus mutant containing a lacZ insertion in the US6 (gD) homologue gene.PMID 7871761Read ↗

Characterization of Marek's disease virus insertion and deletion mutants that lack US1 (ICP22 homolog), US10, and/or US2 and neighboring short-component open reading framesSemantic proximity Read ↗

Horizontal transmission of Marek's disease virus requires US2, the UL13 protein kinase, and gC.Semantic proximity Read ↗

The complete unique long sequence and the overall genomic organization of the GA strain of Marek's disease virusSemantic proximity Read ↗

Retention of oncogenicity by a Marek's disease virus mutant lacking six unique short region genesSemantic proximity Read ↗

High-Level Expression of Marek's Disease Virus Glycoprotein C Is Detrimental to Virus Growth In VitroSemantic proximity Read ↗

Marek's Disease Virus Expresses Multiple UL44 (gC) Variants through mRNA Splicing That Are All Required for Efficient Horizontal TransmissionSemantic proximity Read ↗

Further Analysis of Marek's Disease Virus Horizontal Transmission Confirms That U L 44 (gC) and U L 13 Protein Kinase Activity Are Essential, while U S 2 Is NonessentialSemantic proximity Read ↗

Characterization of LORF11, a unique gene common to the three Marek's disease virus serotypes.Semantic proximity Read ↗

Construction and characterization of an equine herpesvirus 1 glycoprotein C negative mutant.Semantic proximity Read ↗

Glycoproteins E and I of Marek's Disease Virus Serotype 1 Are Essential for Virus Growth in Cultured CellsSemantic proximity Read ↗

Deletions in herpes simplex virus glycoprotein D define nonessential and essential domains.Semantic proximity Read ↗

Retroviral insertional activation in a herpesvirus: transcriptional activation of US genes by an integrated long terminal repeat in a Marek's disease virus cloneSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.