Article
Characterization of a Marek's disease virus mutant containing a lacZ insertion in the US6 (gD) homologue gene.
Virus genes - 1 Sept 1994
Parcells M S, Anderson A S, Morgan R W
Abstract excerpt
We report the construction of a Marek's disease virus (MDV) mutant containing the lacZ gene of Escherichia coli inserted into a homologue of the US6 (glycoprotein D, gD) gene of herpes simplex virus. The mutant was constructed using the high-passage GAatt85 MDV strain as the parent virus, since that strain grows readily in chicken embryo fibroblasts using culture conditions conducive to mutant virus construction....
Topics
- Animals
- Cells, Cultured
- Chick Embryo
- Chickens
- Chromosome Mapping
- DNA Transposable Elements
- Escherichia coli
- Genes, Viral
- Herpesvirus 2, Gallid
- Lac Operon
- Leukocytes
