Article
The role of Hox genes in limb development.
Progress in clinical and biological research - 1 Jan 1993
Morgan B A, Tabin C J
Abstract excerpt
In order to directly test the function of Hox genes in vertebrate limb development, we have employed a replication-competent retroviral vector to express the genes ectopically in developing chick limb buds. It has been hypothesized that the sum of all Hox genes expressed in a developing region forms a "Hox code" which determines the fate of structures arising from that region. When the Hox code of the of the...
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