Relative contributions of levels of initial damage and repair of double-strand breaks to the ionizing radiation-sensitive phenotype of the Chinese hamster cell mutant, XR-V15B. Part II. Neutrons.

Abstract excerpt

We have compared DNA double-strand break (dsb) induction and rejoining, using field-inversion gel electrophoresis, with survival in mutant (XR-V15B) and in wild-type parental (V79B) hamster cell lines after low dose neutron and X-irradiation. We found that neutrons do not appear to induce more dsbs than X-rays and deduce that increased sensitivity to neutrons is therefore not due to a higher initial yield of...

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