Nosocomial Outbreak of Tuberculosis in a Renal Transplant Unit: Application of a New Technique for Restriction Fragment Length Polymorphism Analysis of Mycobacterium tuberculosis Isolates

Abstract excerpt

From January 1990 through February 1991, tuberculosis (TB) developed in 10 renal transplant (RT) patients at one hospital; 5 patients died. Possible nosocomial transmission was investigated. Mycobacterium tuberculosis isolates were compared by restriction fragment length polymorphism (RFLP) by a polymerase chain reaction method. The source case occurred in an RT patient (source) who had posttransplant exposure to...

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