Article
Certain HLA antigens are associated with specific morphologic and cytogenetic subsets of acute myeloid leukemia.
Leukemia - 1 Mar 1995
Joventino L P, Stock W, Lane N J, Daly K M, Mick R, Le Beau M M, Larson R A
Abstract excerpt
Although many associations have been found between specific HLA antigens and an increased susceptibility to various diseases, previous attempts to associate class I and II antigens with acute myeloid leukemia (AML) have been inconclusive, probably due in part to the heterogeneity of AML. We subdivided 165 consecutive adults with AML de novo into distinct clinical, morphological, and cytogenetic subsets and then...
Topics
- Acute Disease
- Adolescent
- Adult
- Aged
- Antigens, Neoplasm
- Antineoplastic Combined Chemotherapy Protocols
- Chromosome Aberrations
- Disease-Free Survival
- Drug Resistance
- Female
- Genetic Predisposition to Disease
