Article
Characterization of growth hormone receptor messenger ribonucleic acid variants in human adipocytes.
The Journal of clinical endocrinology and metabolism - 1 May 2006
Wei Yuhong, Rhani Zakaria, Goodyer Cynthia Gates
Abstract excerpt
CONTEXT: Human GH exerts profound effects on adiposity through its specific receptor, hGHR. Eight hGHR mRNAs are produced by the hGHR gene due to splicing from alternate 5'-untranslated region first exons into a common acceptor site upstream of the start codon in exon 2. Four transcripts (V2, V3, V5, V9) are ubiquitously expressed, whereas the other four (V1, V4, V7, V8) are expressed only in normal postnatal...
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