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Article

Schizophrenia and manic-depression: separate illnesses or a continuum?

Canadian journal of psychiatry. Revue canadienne de psychiatrie - 1 Nov 1994

Lapierre Y D

Abstract excerpt

Kraepelin proposed that schizophrenia and manic-depression were distinct and separable disorders. This hypothesis has been challenged recently by proponents of the "unitary psychosis" theory which posits a continuum from unipolar to bipolar disorder, continuing through schizoaffective and schizophrenic illness. In reviewing symptom cluster data and family studies, the author suggests that there is no compelling...

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PMID: 7874666

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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