Article
Molecular basis of familial growth hormone deficiency.
Hormone research - 1 Jan 1994
Pérez Jurado L A, Argente J
Abstract excerpt
A significant proportion of cases of GH deficiency (5-30%) may be due to genetic causes. At least four Mendelian types of isolated GH deficiency (IGHD) have been delineated based on the mode of inheritance and the degree of GH deficiency: IGHD type IA, autosomal recessive with absent endogenous G...
Topics
- Dwarfism, Pituitary
- Female
- Gene Deletion
- Genes, Dominant
- Genes, Recessive
- Genetic Linkage
- Growth Disorders
- Growth Hormone
- Growth Hormone-Releasing Hormone
- Humans
- Male
- Mutation
- Pedigree