Article
A novel HLA allele, DRB1*1609, identified in the Chinese Han population*.
Tissue antigens - 1 Sept 2005
Miao K R, Pan Q Q, Xue M, Zhou X Y, Fei X M, Tang Y H, Xu R, Zhang J W, Zhao X, Osowski L, Shi W X, Xu A L, Wang C Y, KuKuruga D
Abstract excerpt
A novel human leucocyte antigen-DRB1*16 (HLA-DRB1*16) allele (DRB1*1609) has been identified by sequencing-based typing (SBT) in Chinese Han population. This new allele has identical nucleotide sequence to DRB1*160101 in exon 2, except for a single-nucleotide substitution from A to T at position 127. This change leads to an amino acid change from tyrosine to phenylalanin at residue 47 (Y47F). SBT was performed...
Topics
- Alleles
- Base Sequence
- China
- Exons
- Family Health
- Female
- HLA-DR Antigens
- HLA-DRB1 Chains
- Histocompatibility Testing
- Humans
- Male
- Molecular Sequence Data