Article
Rapid detection and prevalence of the variants of the angiotensinogen gene in patients with essential hypertension.
Journal of internal medicine - 1 Feb 1995
Morise T, Takeuchi Y, Takeda R
Abstract excerpt
OBJECTIVES: The angiotensinogen (AGT) gene has been implicated as a candidate gene of high blood pressure. However, because the variants of the AGT gene are point mutations, it is difficult to detect them in large scale population studies. The aims of this study were to develop a rapid screening method for the point mutations and, using this method, to determine the possible role of the AGT gene variant in high...
Topics
- Adult
- Alleles
- Angiotensinogen
- Base Sequence
- Female
- Humans
- Hypertension
- Japan
- Male
- Middle Aged
- Molecular Sequence Data
- Point Mutation
