Article
Diagnostic criteria for cystic fibrosis in men with congenital absence of the vas deferens.
Medicine - 1 Jan 1995
Durieu I, Bey-Omar F, Rollet J, Calemard L, Boggio D, Lejeune H, Gilly R, Morel Y, Durand D V
Abstract excerpt
The high frequency of cystic fibrosis (CF) mutations in males with absence of vas deferens supported the hypothesis of a primarily genital phenotype of CF disease. To consider the idea of an attenuated form of CF, we investigated 14 men with congenital bilateral aplasia of the vasa deferentia. All patients were consulting for infertility and none was known to have CF. The median age was 30.5 years (range, 20-38...
Topics
- Adult
- Chlorides
- Cystic Fibrosis
- Genetic Carrier Screening
- Genotype
- Humans
- Infertility, Male
- Male
- Sweat
- Vas Deferens