Article
Genetic variation of foot-and-mouth disease virus during persistent infection in cattle.
Virus research - 1 Oct 1994
Malirat V, De Mello P A, Tiraboschi B, Beck E, Gomes I, Bergmann I E
Abstract excerpt
Genetic variation of foot-and-mouth disease virus O1 Campos has been analyzed in consecutive isolates recovered over a one- or two-year period from four cattle with experimental persistent infection. Comparisons of RNase T1 two-dimensional maps and nucleotide sequences of the VP1-coding region revealed a continual, although irregular, increase in the fixation of mutations as the infection progressed. Most changes...
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