Article
Concordance for Hodgkin's disease in identical twins suggesting genetic susceptibility to the young-adult form of the disease.
The New England journal of medicine - 16 Feb 1995
Mack T M, Cozen W, Shibata D K, Weiss L M, Nathwani B N, Hernandez A M, Taylor C R, Hamilton A S, Deapen D M, Rappaport E B
Abstract excerpt
BACKGROUND: Relatives of young adults with Hodgkin's disease are at increased risk of Hodgkin's disease, and lines of evidence implicate both inheritance and environment. METHODS: We have identified and followed 432 sets of twins affected by Hodgkin's disease. The number of cases of Hodgkin's disease observed before the age of 50 years in the healthy monozygotic and dizygotic twins of the patients with Hodgkin's...
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