Transplantation of Cord-Blood Stem Cells into a Patient with Severe Thalassemia

Abstract excerpt

Several different kinds of thalassemia and hemoglobinopathy are prevalent in Southeast Asia.1,2 The frequency of the α-thalassemias reaches 30 to 40 percent in northern Thailand, whereas the β-thalassemias occur at a frequency of 3 to 9 percent. Hemoglobin E, the hallmark hemoglobinopathy of Southeast Asia, occurs at a frequency of 50 to 60 percent at the junction of Thailand, Laos, and Cambodia. Mutation and...

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