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Article

Molecular analysis of the erythropoietin receptor system in patients with polycythaemia vera

1 Dec 1994

Abstract excerpt

Erythropoietin (EPO) is a potent regulator of the viability, proliferation and differentiation of erythroid progenitor cells. Its effect is mediated by binding to the erythropoietin receptor (EPO-R), a member of a new cytokine receptor family. Alterations of the EPO/EPO-R system have recently been shown to be involved in the pathogenesis of familial erythrocytosis and polycythaemia vera (PV). In order to define...

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Identifiers

PMID: 7819104
DOI: 10.1111/j.1365-2141.1994.tb05119.x

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Molecular analysis of the erythropoietin receptor system in patients with polycythaemia veraPMID 7819104Read ↗

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