Article
Mannose-binding protein gene polymorphism in systemic lupus erythematosus.
Arthritis and rheumatism - 1 Jan 1995
Davies E J, Snowden N, Hillarby M C, Carthy D, Grennan D M, Thomson W, Ollier W E
Abstract excerpt
OBJECTIVE: To determine whether an allelic form of mannose-binding protein (MBP) incapable of activating complement is associated with susceptibility to systemic lupus erythematosus (SLE). METHODS: MBP allele frequencies were determined by amplification refractory mutation system-polymerase chain...
Topics
- Adolescent
- Adult
- Aged
- Alleles
- Base Sequence
- Carrier Proteins
- Child
- Complement System Proteins
- Female
- Gene Frequency
- Humans
- Lupus Erythematosus, Systemic
- Male
- Mannose-Binding Lectins
- Middle Aged
- Molecular Sequence Data
- Polymorphism, Genetic