Article
Mannose-binding protein gene polymorphism in systemic lupus erythematosus.
Arthritis and rheumatism - 1 Jan 1995
Davies E J, Snowden N, Hillarby M C, Carthy D, Grennan D M, Thomson W, Ollier W E
Abstract excerpt
OBJECTIVE: To determine whether an allelic form of mannose-binding protein (MBP) incapable of activating complement is associated with susceptibility to systemic lupus erythematosus (SLE). METHODS: MBP allele frequencies were determined by amplification refractory mutation system-polymerase chain reaction in 102 white SLE patients and 136 controls. RESULTS: The MBP allele that is unable to activate complement was...
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