Article
[Apolipoprotein E and Alzheimer dementia. Personal results and brief literature review].
Der Nervenarzt - 1 Nov 1994
Förstl H, Czech C, Sattel H, Geiger-Kabisch C, Besthorn C, Kreger S, Mönning U, Hartmann T, Masters C, Beyreuther K
Abstract excerpt
The apolipoprotein E allele (Apo-E gene) status was determined in 147 individuals from a longitudinal study. 53 satisfied NINCDS-ADRDA criteria for probable or possible Alzheimer's disease (AD), 37 were non-demented healthy controls. 31 patients with AD had one or two Apo-E 4 alleles (phenotypes...
Topics
- Aged
- Aged, 80 and over
- Alleles
- Alzheimer Disease
- Apolipoproteins E
- Chromosomes, Human, Pair 14
- Chromosomes, Human, Pair 19
- Dementia
- Female
- Gene Frequency
- Homozygote
- Humans
- Longitudinal Studies
- Male
- Middle Aged
- Mutation
- Neuropsychological Tests
- Prospective Studies
