Article
Effect of mutations in the -10 region of the phoE promoter in Escherichia coli on regulation of gene expression.
Molecular & general genetics : MGG - 28 Oct 1994
Scholten M, Tommassen J
Abstract excerpt
The phoE promoter region in Escherichia coli contains a -10 region, typical of sigma 70-dependent promoters and, instead of a normal -35 region, a so-called pho box, to which the transcriptional activator phospho-PhoB binds under low phosphate conditions. A second pho box is present upstream of the first one and is required for full expression of phoE during phosphate starvation. To determine whether the lack of...
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