Article
High frequency of the apo epsilon 4 allele in Khoi San from South Africa.
Human genetics - 1 Jan 1995
Sandholzer C, Delport R, Vermaak H, Utermann G
Abstract excerpt
Variation at the apolipoprotein E (apo E) gene locus affects cholesterol concentrations, the risk for atherosclerosis and Alzheimer disease (AD), and is associated with longevity in Caucasians. We have determined apo E gene frequencies and effects on cholesterol levels in Khoi San (Bushmen) from South Africa. The frequency of the apo epsilon 4 allele (0.37), which confers dose-dependent susceptibility to...
Topics
- Adult
- Alleles
- Apolipoproteins E
- Black People
- Cholesterol
- Ethnicity
- Female
- Gene Frequency
- Humans
- Male
- South Africa