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Article

Age-Related Differences In Cell-Mediated Immunity To Varicella-Zoster Virus Among Children And Adults Immunized With Live Attenuated Varicella Vaccine

1 Jan 1995

Abstract excerpt

Live attenuated varicella vaccine elicits protection against varicella-zoster virus (VZV), but adults require two doses to achieve optimal seroconversion rates. To assess the potential role of cell-mediated immunity (CMI), T cell proliferation to VZV antigen was compared in children and adults. Mean stimulation indices (SI) in two cohorts of 39 children tested 6 weeks after vaccination were 28.6 +/- 6.21 and 22.1...

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Identifiers

PMID: 7798653
DOI: 10.1093/infdis/171.1.13

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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