Article
[The detection and study of mitomycin C-induced mutational changes in stable lines of Drosophila melanogaster].
TSitologiia i genetika - 1 Jan 2000
Maksymiv D V, Shcherbata H R, Chernyk Ia I
Abstract excerpt
The influence of mitomycin C on the genetic stability of Drosophila laboratory lines was investigated. This mutagen caused one-locus and multi-loci mutations with high frequencies (approximately 10(-2), 10(-3)) in the first and the second generations. It is locus-specific mutagenesis. In situ hybridization experiments indicated the existence of primary and new sites of location of mobile genetic elements mdg 1,...
Topics
- Animals
- DNA
- DNA Transposable Elements
- Drosophila melanogaster
- Female
- Genotype
- In Situ Hybridization
- Male
- Mitomycin
- Mutation
- X Chromosome
