Article
Accumulation of mutations affecting body weight in inbred mouse lines.
Genetical research - 1 Apr 1995
Caballero A, Keightley P D, Hill W G
Abstract excerpt
The variation from spontaneous mutations for 6-week body weight in the mouse was estimated by selection from a cross of two inbred sublines, C57BL/6 and C57BL/10, separated about 50 years previously from the same inbred line. Selection was practised high and low for 12 generations from the F2, followed by one generation of relaxation. The lines diverged by approximately 1.7 g or 0.7 sd. The additive genetic...
Topics
- Animals
- Body Weight
- Crosses, Genetic
- Mice
- Mice, Inbred C57BL
- Mutation
- Selection, Genetic