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Article

Extraordinary divergence and positive Darwinian selection in a fusagenic protein coating the acrosomal process of abalone spermatozoa.

Proceedings of the National Academy of Sciences of the United States of America - 23 May 1995

Swanson W J, Vacquier V D

Abstract excerpt

During fertilization in marine invertebrates, fusion between sperm and egg cell membranes occurs at the tip of the sperm acrosomal process. In abalone sperm the acrosomal process is coated with an 18-kDa protein. In situ, this protein has no effect on the egg vitelline envelope, but in vitro it is a potent fusagen of liposomes. Thus, the 18-kDa protein may mediate membrane fusion between the gametes, a step in...

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PMID: 7761431
DOI: 10.1073/pnas.92.11.4957
PMCID: PMC41826

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