Article
Characterization of mutants of the vitamin D-binding protein/group-specific component: molecular evolution of GC*1A2 and GC*1A3, common in some Asian populations.
Human genetics - 1 May 1995
Yuasa I, Kofler A, Braun A, Umetsu K, Bichlmaier R, Kammerer S, Cleve H
Abstract excerpt
A well defined polymorphism of vitamin D-binding/group-specific component (GC) residues in exon 11. To characterize the molecular basis of GC*1A2 and GC*1A3, common in some Asian populations, we analyzed all coding exons amplified by the polymerase chain reaction. GC*1F was divided into GC*1FC an...
Topics
- Alleles
- Base Sequence
- Biological Evolution
- DNA
- DNA Primers
- Exons
- Female
- Humans
- Japan
- Male
- Molecular Biology
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Polymorphism, Single-Stranded Conformational
- Vitamin D-Binding Protein