Article
Characterization of mutants of the vitamin D-binding protein/group-specific component: molecular evolution of GC*1A2 and GC*1A3, common in some Asian populations.
Human genetics - 1 May 1995
Yuasa I, Kofler A, Braun A, Umetsu K, Bichlmaier R, Kammerer S, Cleve H
Abstract excerpt
A well defined polymorphism of vitamin D-binding/group-specific component (GC) residues in exon 11. To characterize the molecular basis of GC*1A2 and GC*1A3, common in some Asian populations, we analyzed all coding exons amplified by the polymerase chain reaction. GC*1F was divided into GC*1FC and GC*1FT by a C-T transition in the third nucleotide of the codon (TGC/T) for cysteine283 in exon 8. The sequencing of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.