Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CAG repeat length variation in sperm from a patient with Kennedy's disease.

Human molecular genetics - 1 Feb 1995

Zhang L, Fischbeck K H, Arnheim N

Abstract excerpt

Using a modified sperm typing protocol, the mutation frequency of the CAG repeat region at the androgen receptor locus has been measured using a rare semen sample from an individual with spinal and bulbar muscular atrophy (SBMA). Among 258 X chromosome-containing sperm, 19% had a repeat number eq...

Topics

Alleles
DNA
Humans
Lymphocytes
Male
Middle Aged
Muscular Atrophy, Spinal
Polymerase Chain Reaction
Receptors, Androgen
Repetitive Sequences, Nucleic Acid
Spermatozoa

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 7757084
DOI: 10.1093/hmg/4.2.303

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7757084-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CAG repeat length variation in sperm from a patient with Kennedy's disease.PMID 7757084Read ↗

Phenotypic manifestations associated with CAG-repeat expansion in the androgen receptor gene in male patients and heterozygous females: a clinical and molecular study of 30 families.Semantic proximity Read ↗

Kennedy's disease: a clinicopathologic correlation with mutations in the androgen receptor gene.Semantic proximity Read ↗

Moderate instability of the trinucleotide repeat in spino bulbar muscular atrophy.Semantic proximity Read ↗

Studying human mutations by sperm typing: instability of CAG trinucleotide repeats in the human androgen receptor gene.Semantic proximity Read ↗

Diversity in the androgen receptor CAG repeat has been shaped by a multistep mutational mechanism.Semantic proximity Read ↗

Meiotic stability and genotype-phenotype correlation of the trinucleotide repeat in X-linked spinal and bulbar muscular atrophy.Semantic proximity Read ↗

Early onset and novel features in a spinal and bulbar muscular atrophy patient with a 68 CAG repeatSemantic proximity Read ↗

Polymorphic CAG repeat length in the androgen receptor gene and association with neurodegeneration in a heterozygous female carrier of Kennedy's disease.Semantic proximity Read ↗

Wide range of reduced penetrance alleles in spinal and bulbar muscular atrophy: a model-based approach.Semantic proximity Read ↗

Somatic instability of the androgen receptor CAG repeat in a normal female.Semantic proximity Read ↗

Single sperm analysis of the trinucleotide repeats in the Huntington's disease gene: quantification of the mutation frequency spectrum.Semantic proximity Read ↗

Kennedy disease in two sisters with biallelic CAG expansions of the androgen receptor gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.