Article
Protein structure refinement based on paramagnetic NMR shifts: applications to wild-type and mutant forms of cytochrome c.
Protein science : a publication of the Protein Society - 1 Feb 1995
Gochin M, Roder H
Abstract excerpt
A new approach to NMR solution structure refinement is introduced that uses paramagnetic effects on nuclear chemical shifts as constraints in energy minimization or molecular dynamics calculations. Chemical shift differences between oxidized and reduced forms of horse cytochrome c for more than 3...
Topics
- Cytochrome c Group
- Heme
- Iron
- Magnetic Resonance Spectroscopy
- Models, Molecular
- Mutation
- Oxidation-Reduction
- Protein Conformation
- Protein Structure, Tertiary
- Protons