Article
A new B18 sequence (B*1802) from Asian individuals.
Human immunology - 1 Jan 1995
Lin L, Tokunaga K, Ishikawa Y, Kashiwase K, Nakajima F, Nishimura M, Kuwata S, Akaza T, Tadokoro K, Shibata Y
Abstract excerpt
A new HLA-B18 allele (B*1802) derived from a Thai individual was sequenced. Comparison of this B18 nucleotide sequence with the published B*1801 sequence indicated that this Asian B18 allele has a nucleotide sequence different from that of B*1801. Three nucleotide changes were observed in exon 3, in which two substitutions at codon 97, AGG in B*1801 to AAT in the B*1802, result in an amino acid change from...
Topics
- Alleles
- Amino Acid Sequence
- Asian People
- Base Sequence
- Codon
- DNA Mutational Analysis
- Exons
- Gene Frequency
- HLA-B Antigens
- HLA-B18 Antigen
- Haplotypes
- Humans
