Article
Ethnic differences in allele frequencies of two microsatellite markers closely linked to the locus for polycystic kidney disease 1 (PKD1).
Human heredity - 1 Jan 2000
Wang H, Kuwata S, Juji T, Yanagisawa M, Tokunaga K, Horie S, Higashihara E, Kurokawa K, Yoshikura H, Shibata Y
Abstract excerpt
Two microsatellite markers, D16S283 and D16S284, closely linked to the locus of autosomal polycystic kidney disease (PKD1), were amplified in a Japanese population sample by the polymerase chain reaction to investigate differences in allele frequencies between Japanese and Caucasian populations. Ten D16S283 alleles and four D16S284 alleles were discerned among 53 Japanese. The observed heterozygosities of D16S283...
Topics
- Alleles
- Asian People
- Base Sequence
- DNA, Satellite
- Gene Frequency
- Genetic Markers
- Humans
- Japan
- Molecular Sequence Data
- Polycystic Kidney, Autosomal Dominant
- Polymerase Chain Reaction