Separation of sequence requirements for HSV-1 Vmw110 multimerisation and interaction with a 135-kDa cellular protein.

doi:10.1006/viro.1995.1241

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Article

Separation of sequence requirements for HSV-1 Vmw110 multimerisation and interaction with a 135-kDa cellular protein.

Virology - 10 May 1995

Meredith M, Orr A, Elliott M, Everett R

Abstract excerpt

Herpes simplex virus type 1 immediate-early polypeptide Vmw110 (ICP0) is a general transactivator of gene expression in transfection assays and is required for the fully efficient onset of viral lytic replication. It has also been implicated in the process of viral reactivation from latency. Its mechanism of action is unknown, but any involvement in latency requires interactions between viral and host factors. We...

Topics

Animals
Baculoviridae
Cell Line
Cricetinae
Herpesvirus 1, Human
Immediate-Early Proteins
Molecular Weight
Mutation
Neoplasm Proteins
Nuclear Proteins
Protein Conformation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Proteins

Spodoptera

Transcription Factors

Tumor Suppressor Proteins

Ubiquitin-Protein Ligases

Virus Activation

Source

Open in PubMed

Identifiers

PMID: 7747467
DOI: 10.1006/viro.1995.1241

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7747467-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Separation of sequence requirements for HSV-1 Vmw110 multimerisation and interaction with a 135-kDa cellular protein.PMID 7747467Read ↗

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