Article
Neurobehavioral characteristics of CGG amplification status in fragile X females.
American journal of medical genetics - 15 Dec 1994
Thompson N M, Gulley M L, Rogeness G A, Clayton R J, Johnson C, Hazelton B, Cho C G, Zellmer V T
Abstract excerpt
Neurobehavioral correlates of CGG amplification were studied in 17 nonretarded adult female carriers of fragile X syndrome. The results revealed a significant relationship between IQ and the number of CGG repeats in the 5' untranslated region of the FMR1 gene. Women with a full mutation (> 200 CG...
Topics
- Adult
- Base Sequence
- DNA
- Female
- Fragile X Mental Retardation Protein
- Fragile X Syndrome
- Genetic Carrier Screening
- Humans
- Intelligence
- Male
- Memory
- Mutation
- Nerve Tissue Proteins
- Neuropsychological Tests
- RNA-Binding Proteins
- Reaction Time
- Reference Values
- Repetitive Sequences, Nucleic Acid